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The study included five pigs, of which three were implanted with a liver scaffold seeded with human vascular cells and porcine hepatocytes. The successful completion of these transplants demonstrates the efficacy of bioengineering whole organs through the process of decellularization and recellularization, an exciting advancement given the chronic shortage of donor organs for liver failure patients. The results, published in Nature Communications Biology, showed the pigs that received the bioengineered livers maintained detectable hepatic health in the graft, sustained blood perfusion, and demonstrated early liver function post transplantation.

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It utilized decellularized porcine liver scaffolds recellularized with human vascular cells and porcine hepatocytes, which were implanted into pigs suffering acute liver failure. The transplant was part of a preclinical study in collaboration with researchers at Mayo Clinic, designed to assess the initial transplantation and functionality of a bioengineered liver in an acute liver failure model. announced it has successfully completed the first ever heterotopic implant of its bioengineered liver transplant into a large animal.

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Miromatrix Announces the First Successful Transplant of A Bioengineered Whole Organ in A Large Animal He is also a certified public accountant. Kellogg School of Management at Northwestern University. Douglas graduated from the University of Wisconsin–Milwaukee with an accounting degree and earned a Master of Business Administration degree specializing in analytical finance and marketing from the J.L. Prior to Abbott, he worked at PricewaterhouseCoopers providing audit and transaction services. Douglas worked at Abbott Laboratories in the corporate financial planning division and global pharmaceutical operations division (now AbbVie). Douglas was a managing director and the longest tenured investment banker on the biotechnology team. At the time of his departure from Piper Sandler, Mr. Since 2005, Jim worked at Piper Sandler in the healthcare investment banking group, advising biotechnology and medical technology companies on M&A and financing transactions, as well as providing a broad range of strategic guidance. Douglas joins the Miromatrix team with over 25 years of relevant work experience in investment banking, industry, and public accounting. Douglas will succeed Brian Niebur, who will continue to serve Miromatrix as the Vice President of Finance. As CFO, Jim will lead Miromatrix’s finance organization and oversee all financial activities of the corporation. announced the appointment of Jim Douglas as the Company’s new Chief Financial Officer (CFO) effective March 1, 2022. Miromatrix Names Jim Douglas as New Chief Financial Officer Lake's research expertise includes liver allocation, predictors of outcomes following liver transplantation, and the development of new treatments for patients with liver disease. He is also the former editor of the journal Liver Transplantation. Lake has also held leadership roles in the American Association for the Study of Liver Disease and the International Liver Transplantation Society. Lake is the past President of both the United Network for Organ Sharing (UNOS) and the American Society of Transplant Physicians. In addition to his work at the University of Minnesota, Dr. Lake will serve as Miromatrix's Medical Director while remaining in his current roles at the University. He is also the Executive Medical Director for Solid Organ Transplantation at the University of Minnesota Medical Center. Lake is a Professor of Surgery and Medicine and the Chief of Hepatology in the Department of Medicine at theUniversity of Minnesota. as the Company's new Medical Director.Dr. announced that it has appointed Jack Lake, M.D.

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Appoints Jack Lake, M.D., as Medical Director












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